New York Giants at San Francisco (-3.5, 42.5): Giants are traveling coast to coast after an extremely emotional win and facing one of the toughest defenses in the NFL.
The Predicted Score: San Francisco Wins 24-13
The Picks: San Francisco -3.5 and Under 42.5
St. Louis at Cleveland (-2.5, 36.5): Steven Jackson can run with the best of them, and the Browns were thrashed for 100 yards by not one, but two Texans last week.
The Pick: St. Louis +2.5
Arizona at Philadelphia (-14, 46.5): I will probably regret this pick, but I love the situation. Cardinals are traveling east after a huge OT win, and the Eagles get to face a weak offense with no run game.
The Pick: Eagles -14
New Orleans at Atlanta (-1, 49.5): As long as Atlanta sticks to their winning formula and grinds it with Turner, they should be able to control the game and the Saints.
The Pick: Atlanta -1