Green Bay at Detroit (+6.5, 55.5): Short week or not, you can't convince me otherwise that each team doesn't score at least 4 TDs.
The Pick: Over 55.5
San Francisco at Baltimore (-3.5, 40): In the Harbaugh family game, I have to roll with experience. On the road, coast to coast, on a short week, against the best defense they've faced all year, the 49ers will come back to Earth.
The Pick: Ravens -3.5
Miami at Dallas (-7, 44.5): Wrong place, wrong time for Miami. Dallas is the hotter of the three-win-streaking teams, and the Cowboys own Thanksgiving.
The Pick: Dallas -7
Houston at Jacksonville (+3.5, 37.5): The Texans could run the ball with Foster and Tate the whole game and win it by 14. Leinart will have Andre to toss the ball up to, so it's not as if the offense went down with Schaub.
The Pick: Houston -3.5
Denver at San Diego (-6, 43.5): A division matchup with lots of rush attempts, one D that has been solid (Broncos), and one D that doesn't want to fall as the latest Tebow victim.
The Pick: Under 43.5
Buffalo at New York Jets (-9, 41.5): It takes offenses to score multiple TDs (usually), and these two teams have a combined total average of only 27.3ppg over their past three games.
The Pick: Under 41.5
Minnesota at Atlanta (-9.5, 44): The Vikings have lost their only offensive weapon with Peterson out, and their defense struggles on the road.
The Pick: Atlanta -9.5